St Louis: Emerging Hub for Innovative Machine Learning Enterprises

Welcome to the latest installation of our Futurology series where we dive deep into the heartland of the U.S., St. Louis, Missouri. This thriving Midwestern hub represents an intersection of culture, tradition and progressive thinking, framed by the iconic Gateway Arch. Known for its BBQ, breweries and baseball, St. Louis is also home to a burgeoning tech scene with an emphasis on machine learning technologies. Here, we highlight the efforts of companies that are leveraging AI, Machine Learning, and related technologies to disrupt various industries and present futuristic solutions for modern problems.

The digital boom of the 21st Century brought with it the evolution of artificial intelligence (AI) and machine learning, which are technologies that rely on algorithms to make predictions or decisions without being explicitly programmed to perform certain tasks. Now, St. Louis-based companies are harnessing AI and machine learning capabilities to innovate in fields like customer service, collectible verification, patent searching, and health care, offering promising ground for their prospects.

Here, we take a closer look at these cutting-edge companies, illuminating their mission, work, significance, and what they bring to the vibrant tech community of St. Louis. Prepare to journey into the heart of America’s Heartland tech scene as we examine ten companies passionately embracing the transformative power of machine learning and artificial intelligence.


Balto, an AI enterprise founded by Chris Kontes, Davidson Girard, and Marc Bernstein, is revolutionizing the contact center industry. Balto utilizes machine learning to guide over 150 million calls, presenting real-time recommendations to agents, preventing negative customer experiences, compliance errors, and missed sales opportunities. A trusted partner of National General Insurance, eHealth, American Homes for Rent, and many more, Balto is continuously growing its clientele on both a national and international level. Connect with Balto on Twitter, Facebook, and Linkedin.


Disruptel is a pioneer in the visual AI industry, interpreting video and image content accurately. This enables viewers to engage deeply with their content, asking questions, and even purchasing products directly from their screens. Founded by Alex Quinn and John Lowrey in 2017, Disruptel has built strong partnerships with device manufacturers, streaming services, and operating systems. For more on Disruptel, follow them on Twitter, Facebook, and Linkedin.

Olio City


BLOCK id is a St. Louis company that operates in the intersection of AI, Information Services, Information Technology, and Machine Learning. More information can be found on their website and Linkedin.


Reliancy, a company with a bio coming soon. To learn more, visit their website and follow them on Twitter, Facebook, and Linkedin.

Through this exploration of St. Louis’ machine learning sector, it’s clear that Midwestern innovation and entrepreneurship are alive and well. These companies represent the potential for this burgeoning sector to continue to shape the future in unimaginable ways, potentially bringing us closer to a world where technology interactively assists us in our daily tasks, making life easier, safer, and more efficient.

Written by Mark Smith

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