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98 Most Innovative Chicago Based Artificial Intelligence Companies

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This article showcases our top picks for the best Chicago based Artificial Intelligence companies. These startups and companies are taking a variety of approaches to innovating the Artificial Intelligence industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

Top Chicago Artificial Intelligence Startups

Data sourced from Crunchbase and SemRush.

Tempus

Tempus

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Tempus is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.

4Degrees

4Degrees

Crunchbase Website Twitter Facebook Linkedin

AI-enabled relationship management platform, built for relationship driven industries.

4Degrees

Uptake Technologies

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Uptake Technologies designs and develops enterprise software.

4Degrees

QuillBot

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QuillBot is a startup developing an AI writing tool that reconstructs its user’s writing to be more clear and concise.

4Degrees

Arturo

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Arturo is a deep learning spin-out from a Fortune 500 company focused on delivering highly accurate measurement and predictive data.

4Degrees

Narrative Science

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Narrative Science creates software that writes stories from enterprise data to drive understanding and results.

4Degrees

ModelOp

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Pioneer of ModelOps software enabling enterprises to address the critical governance and scale challenges in operationalizing AI/ML models

4Degrees

FarEye

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FarEye is a low-code, Intelligent Delivery Management Platform designed for a better delivery experience for everyone.

4Degrees

simMachines

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simMachines provides similarity-oriented solutions for advanced analytics.

4Degrees

Clearstep

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Clearstep is a platform for health systems to provide a complete and digital front door experience.

4Degrees

Odeza

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Automated Concierge Messaging Platform for Healthcare

4Degrees

Varuna

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Varuna provides alerts, recommendations, and predictions to help water utility leaders to effectively manage a water system.

4Degrees

Blinkfire Analytics

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Blinkfire Analytics uses AI and computer vision to optimize the sponsorship marketplace between creators, and their sponsors.

4Degrees

Anthill AI

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Anthill enables companies to retain, engage, and develop employees when work happens away from the office.

4Degrees

Reveal

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Reveal is a global provider of eDiscovery, compliance and risk technology.

4Degrees

rMark Bio

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rMark Bio delivers intelligence solutions to the life science industry.

4Degrees

Monument

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Monument backs up and automatically organizes your precious memories effortlessly.

4Degrees

ImmersiveTouch

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ImmersiveTouch is using the latest advancements in computer vision, AI and AR/VR to develop FDA cleared medical technology.

4Degrees

SupplyHive

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SupplyHive™ Supplier Performance Software

4Degrees

Shurpa

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Shurpa is an SaaS platform to manage compliance, scheduling, and logistics of in-home healthcare services.

4Degrees

NexLP

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NexLP provides a predictive intelligence software solution that turns electronic data into patterns and stories.

4Degrees

Koios Medical

Crunchbase Website Twitter Facebook Linkedin

Koios Medical is a leading healthcare into the era of machines & supporting physicians in delivering exceptional care.

4Degrees

Heretik

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Heretik is a Chicago-based software company using machine learning to make the contract review process easier and smarter.

4Degrees

Lab Me Analytics

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Lab Me Analytics provides direct-to-consumer healthcare and blood analytics.

4Degrees

WealthBlock

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WealthBlock is a technology firm established in 2018 and proudly based in Chicago, Illinois.

4Degrees

MessageControl

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Human Layer Email and Messaging Security

4Degrees

Inference Analytics, Inc.

Crunchbase Website Twitter Facebook Linkedin

Deep tech company using leading edge AI based work on text and images to assist diagnosis in dentistry and medicine.

4Degrees

Murmur

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Customer Data Platform helps brands to explore audiences in real-world, connect with them in real-time via car-top billboards.

4Degrees

Strike Social

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The global leader in AI for social advertising

4Degrees

ConceptDrop

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ConceptDrop matches brands with an invite-only community of creative professionals.

4Degrees

SwayBrand

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SwayBrand’s AI-powered platform creates authentic influencer micro-marketing moments.

4Degrees

Nevermaps

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We help SMBs enter Conversational Marketing in 1 week with our Turn-Key AI Assistants and Human Sales Agents.

4Degrees

Verboso

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Verboso develops an open-source database of impaired speech sounds for children.

4Degrees

Iris Light Technologies

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Iris Light Technologies is an electronic company that empowers the cloud through breakthrough on-chip laser technology.

4Degrees

Esquify

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Esquify is a software company that provides AI automation workforce management solutions for legal review.

4Degrees

Pymedix

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Pymedix is building fully-automated machine perception technologies that move medical imaging forward.

4Degrees

p3rceive

Crunchbase Website Twitter Facebook Linkedin

Sales simulation and modeling engine.

4Degrees

Speciate AI

Crunchbase Website Twitter Facebook Linkedin

Speciate AI provides an AI driven solution to help companies understand what the market feels about their products and identify ways to grow

4Degrees

Stats Perform

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Stats Perform is the market sports technology company across media and tech, betting, and team performance.

4Degrees

Data Products LLC

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Data Science Consulting

4Degrees

Etta Epidermis

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Skin and STD/STI Diagnostic Mobile App (AI/AR)

4Degrees

Ashling Partners

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Ashling Partners is an award-winning service provider in the rapidly growing intelligent automation market.

4Degrees

Sensefolio

Crunchbase Website Twitter Facebook Linkedin

Artificial Intelligence ESG Data startup specialized in socially responsible investment #AI #ESG #SRI #AM #FinTech

4Degrees

10th Magnitude

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10th Magnitude is a Digital Transformation services firm, helping organizations innovate, lead, and disrupt.

4Degrees

AiRo Digital Labs

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AiRo Digital Labs is an emerging tech solutioning company specializing in transforming healthcare ecosystem

4Degrees

Powerupcloud Technologies

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Powerupcloud is a cloud technology company with product & services in cloud migrations, managed cloud and AI solutions.

4Degrees

Socian Technologies

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SaaS, Hardware, Software

4Degrees

SmarterCloud

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SmarterCloud is a cybersecurity platform that isolates and secures customer data.

4Degrees

Strong Analytics

Crunchbase Website Twitter Facebook Linkedin

Data Science & Machine Learning Consultancy

4Degrees

Intelligent Flying Machines, Inc.

Crunchbase Website Twitter Facebook Linkedin

Intelligent Flying Machines develops systems that maximize inventory accuracy and unleash productivity in the workforce.

4Degrees

HoloSurgical Inc.

Crunchbase Website Twitter Facebook Linkedin

HOLOSURGICAL is a Digital Surgery company focused on improving patient outcomes by bringing machine learning to the operating room

4Degrees

Qlarity Imaging

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Qlarity Imaging offers AI to improve patient care by enhancing the diagnostic insights available to radiologists.

4Degrees

Shortest Track Company

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Shortest Track manages and accelerates the intelligence supply chain for business executives.

4Degrees

BotPenguin

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BotPenguin is an AI-powered chatbot platform.

4Degrees

Riviter

Crunchbase Website Twitter Facebook Linkedin

Riviter helps brands see and serve the people who love them with AI- and visual search-powered intelligence from social images and video.

4Degrees

Tercero Technologies

Crunchbase Website Twitter Facebook Linkedin

Advanced Edge Artificial Intelligence

4Degrees

Neural Trend

Crunchbase Website Twitter Facebook Linkedin

Neural Trend is an AI + big data to shorten the gap between retail supply and consumer demand.

4Degrees

Altris.AI

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SaaS, Mobile App, ophthalmology deep learning platform for automatic, quantitative analysis and detection retinal diseases.

4Degrees

LAGOM

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At LAGOM, we are working for making the world a better place with the power of AI and high technologies.

4Degrees

DemandWorks Media

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DemandWorks’ unique lead generation programs enable you to deliver your content, to the right buyer, at the right time, on any device.

4Degrees

GliaLab

Crunchbase Website Twitter Facebook Linkedin

GliaLab is develop innovative data-driven AI technology solutions for the healthcare industry and beyond.

4Degrees

7QUBES

Crunchbase Website Twitter Facebook Linkedin

SaaS, FinTech, Distributed Ledger Technology, Blockchain, AI

4Degrees

Nousot

Crunchbase Website Twitter Facebook Linkedin

Nousot develops machine learning products to deliver predictive analytics as a service in the field of data science.

4Degrees

Cognitive AI Technologies

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Cognitive AI Technologies develops Carloudy, a head-up display for cars.

4Degrees

FreightFriend

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Cloud-based, AI-powered truckload procurement software

4Degrees

Talent Intelligence

Crunchbase Website Twitter Facebook Linkedin

Talent Intelligence is now recruiting recent college grads for full-time Research positions.

4Degrees

DaVinci

Crunchbase Website Twitter Facebook Linkedin

Hardware, Flying Taxi, Transportation, AI, Autonomous Vehicles

4Degrees

Logic Pursuits

Crunchbase Website Twitter Facebook Linkedin

Logic Pursuits is an analytics company and premier artificial intelligence solutions provider.

4Degrees

INTELLIC.AI

Crunchbase Website Twitter Facebook Linkedin

Saas, Clinical Data, Clinical Prediction Models, Validation, Development, Intelligence, Predictive Analytics

4Degrees

mHealthCoach

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mHealthCoach is a care coordination smart platform that enables physician practices to improve revenue and patient outcomes in the process.

4Degrees

Zenn.ai

Crunchbase Website Twitter Facebook Linkedin

AI-Powered Deal Execution Technology for B2B Sales Teams

4Degrees

Aboriginal Armadillo

Crunchbase Website Twitter Facebook Linkedin

Startup focused on Natural Language Generation and Image Processing.

4Degrees

Quiddity Solutions, LLC.

Crunchbase Website Twitter Facebook Linkedin

Healthcare IT Software to calculate provider cost, patient cost, and payer reimbursements in real-time, at the point of treatment planning.

4Degrees

Logical Information Machines

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Logical Information Machines offers products for analyzing data.

4Degrees

LR Data Science

Crunchbase Website Twitter Facebook Linkedin

At LR Data Science, we run quick audits on organizations wanting to get their share of the booming Online Market.

4Degrees

Digital Authority

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DAP is a fully integrated digital agency that helps businesses grow by combining data-driven insights with creative problem solving.

4Degrees

ProManage

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ProManage is the technology company working on IIoT, AR, AI technology areas for manufacturing operations management.

4Degrees

Emerging Insider

Crunchbase Website Twitter Facebook Linkedin

Insight driven marketing and communications agency, with a focus on emerging media and technology.

4Degrees

Language.ai

Crunchbase Website Twitter Facebook Linkedin

NLP / ML consulting and related SaaS linguistic annotation solutions.

4Degrees

Temporal Games

Crunchbase Website Twitter Facebook Linkedin

Game Development, AI Research and Deployment

4Degrees

StataPile

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StataPile is an artificial intelligence platform that improves sales and service performance by analyzing customer interaction.

4Degrees

Arch Analytics

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Technology consulting firm that helps companies launch custom artificial intelligence solutions faster

4Degrees

Netrolix, LLC

Crunchbase Website Twitter Facebook Linkedin

AI, Machine Learning, Software Defined Networking and Orchestration

4Degrees

Deeproots

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Deeproots make Artificially Intelligent Software that could be retrofitted to agriculture vehicles like tractors to make them autonomous.

4Degrees

Hyperlocal

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Event Intelligence Platform

4Degrees

Enlistics

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Enlistics is a hiring startup that uses advanced statistics and machine learning to algorithmically match applicants & businesses.

4Degrees

AG

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AG is a staffing solutions agency that delivers artificial intelligence, automation, data analytics and client relations services.

4Degrees

homebldr

Crunchbase Website Twitter Facebook Linkedin

Real Estate Investment and Renovation Evaluation Platform

4Degrees

7 Senses Labs

Crunchbase Website Twitter Facebook Linkedin

Story-based Adaptive Learning Solutions for Children

4Degrees

Oscillas Technologies

Crunchbase Website Twitter Facebook Linkedin

Application development and machine learning

4Degrees

Commoot

Crunchbase Website Twitter Facebook Linkedin

Commoot Brings Awareness the the Road by Utilizing Unused Ad Space on the Sides and Back of Trucking Trailers.

4Degrees

ΛDΛPTRΛCK

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Driving impactful behaviors with personalized AI for work+life.

4Degrees

botsensei

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A hands-on approach to learning self driving car technologies

4Degrees

Traekam

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Musician A.I. Digital Twins that personalize each fan’s journey, engagement, and conversation.

4Degrees

Serdoo

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Serdoo is a multi channel help desk system empowered by artificial intelligence.

4Degrees

Bitnary

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Bitnary is an AI powered chatbot that monitors the crypto markets.

4Degrees

EthVentures

Crunchbase Website Twitter Facebook Linkedin

Blockchain. Artificial Intelligence. Digital Currency.

Written by Mark Smith

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