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101 Most Innovative Illinois Based Artificial Intelligence Companies

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This article showcases our top picks for the best Illinois based Artificial Intelligence companies. These startups and companies are taking a variety of approaches to innovating the Artificial Intelligence industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

Top Illinois Artificial Intelligence Startups

Data sourced from Crunchbase and SemRush.

Tempus

Tempus

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Tempus is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.

4Degrees

4Degrees

Crunchbase Website Twitter Facebook Linkedin

AI-enabled relationship management platform, built for relationship driven industries.

4Degrees

Uptake Technologies

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Uptake Technologies designs and develops enterprise software.

4Degrees

QuillBot

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QuillBot is a startup developing an AI writing tool that reconstructs its user’s writing to be more clear and concise.

4Degrees

Arturo

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Arturo is a deep learning spin-out from a Fortune 500 company focused on delivering highly accurate measurement and predictive data.

4Degrees

Narrative Science

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Narrative Science creates software that writes stories from enterprise data to drive understanding and results.

4Degrees

ModelOp

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Pioneer of ModelOps software enabling enterprises to address the critical governance and scale challenges in operationalizing AI/ML models

4Degrees

Samya.AI

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Samya.AI operates as a revenue growth AI company that brings the power of deep learning.

4Degrees

Convr

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Convr empowers commercial insurance carriers with frictionless underwriting to enable optimal efficiency.

4Degrees

FarEye

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FarEye is a low-code, Intelligent Delivery Management Platform designed for a better delivery experience for everyone.

4Degrees

simMachines

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simMachines provides similarity-oriented solutions for advanced analytics.

4Degrees

Clearstep

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Clearstep is a platform for health systems to provide a complete and digital front door experience.

4Degrees

Odeza

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Automated Concierge Messaging Platform for Healthcare

4Degrees

Varuna

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Varuna provides alerts, recommendations, and predictions to help water utility leaders to effectively manage a water system.

4Degrees

Blinkfire Analytics

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Blinkfire Analytics uses AI and computer vision to optimize the sponsorship marketplace between creators, and their sponsors.

4Degrees

Anthill AI

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Anthill enables companies to retain, engage, and develop employees when work happens away from the office.

4Degrees

Reveal

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Reveal is a global provider of eDiscovery, compliance and risk technology.

4Degrees

rMark Bio

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rMark Bio delivers intelligence solutions to the life science industry.

4Degrees

EarthSense, Inc.

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Agricultural Intelligence for a Sustainable Planet

4Degrees

Monument

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Monument backs up and automatically organizes your precious memories effortlessly.

4Degrees

ImmersiveTouch

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ImmersiveTouch is using the latest advancements in computer vision, AI and AR/VR to develop FDA cleared medical technology.

4Degrees

SupplyHive

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SupplyHive™ Supplier Performance Software

4Degrees

Shurpa

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Shurpa is an SaaS platform to manage compliance, scheduling, and logistics of in-home healthcare services.

4Degrees

NexLP

Crunchbase Website Twitter Facebook Linkedin

NexLP provides a predictive intelligence software solution that turns electronic data into patterns and stories.

4Degrees

Tackle AI

Crunchbase Website Twitter Facebook Linkedin

Tackle AI is an algorithms and neural network that automatically discover data on any type of document or image.

4Degrees

Koios Medical

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Koios Medical is a leading healthcare into the era of machines & supporting physicians in delivering exceptional care.

4Degrees

Autobon AI

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Autobon is pioneering DeliveryOS – a fully automated freight shipping platform for those who ship, manage, or transport high-value products.

4Degrees

Heretik

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Heretik is a Chicago-based software company using machine learning to make the contract review process easier and smarter.

4Degrees

Entigenlogic

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Entigenlogic is an artificial intelligence software company.

4Degrees

Lab Me Analytics

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Lab Me Analytics provides direct-to-consumer healthcare and blood analytics.

4Degrees

WealthBlock

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WealthBlock is a technology firm established in 2018 and proudly based in Chicago, Illinois.

4Degrees

Click Deal Buy!

Crunchbase Website Twitter Facebook Linkedin

Click Deal Buy! specializes in the fields of artificial intelligence, machine learning, big data, and analytics.

4Degrees

Sibel Health

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Sibel Health develops an advanced neonatal epidermal system designed for wireless vital signs monitoring.

4Degrees

MessageControl

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Human Layer Email and Messaging Security

4Degrees

Motion AI

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Motion AI is a software company that develops and “trains” chatbots.

4Degrees

Inference Analytics, Inc.

Crunchbase Website Twitter Facebook Linkedin

Deep tech company using leading edge AI based work on text and images to assist diagnosis in dentistry and medicine.

4Degrees

Kokomo 24/7

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Public Safety Cloud Platform with modules – AI-driven Incident Management, Emergency Operation Center, and Anonymous Reporting

4Degrees

Murmur

Crunchbase Website Twitter Facebook Linkedin

Customer Data Platform helps brands to explore audiences in real-world, connect with them in real-time via car-top billboards.

4Degrees

Strike Social

Crunchbase Website Twitter Facebook Linkedin

The global leader in AI for social advertising

4Degrees

ConceptDrop

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ConceptDrop matches brands with an invite-only community of creative professionals.

4Degrees

Jovian Technologies

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AI SaaS platform for Food & Beverage Competitive Intelligence & Consumer data Analytics

4Degrees

SwayBrand

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SwayBrand’s AI-powered platform creates authentic influencer micro-marketing moments.

4Degrees

Acer Innovation

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Acer Innovation is a global analytics firm leveraging data science to help Fortune 500 firms.

4Degrees

Nevermaps

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We help SMBs enter Conversational Marketing in 1 week with our Turn-Key AI Assistants and Human Sales Agents.

4Degrees

Verboso

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Verboso develops an open-source database of impaired speech sounds for children.

4Degrees

Iris Light Technologies

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Iris Light Technologies is an electronic company that empowers the cloud through breakthrough on-chip laser technology.

4Degrees

Esquify

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Esquify is a software company that provides AI automation workforce management solutions for legal review.

4Degrees

Pymedix

Crunchbase Website Twitter Facebook Linkedin

Pymedix is building fully-automated machine perception technologies that move medical imaging forward.

4Degrees

p3rceive

Crunchbase Website Twitter Facebook Linkedin

Sales simulation and modeling engine.

4Degrees

Speciate AI

Crunchbase Website Twitter Facebook Linkedin

Speciate AI provides an AI driven solution to help companies understand what the market feels about their products and identify ways to grow

4Degrees

Stats Perform

Crunchbase Website Twitter Facebook Linkedin

Stats Perform is the market sports technology company across media and tech, betting, and team performance.

4Degrees

Vitrix Health

Crunchbase Website Twitter Facebook Linkedin

We built an oral disease screening platform using AI and imaging to allow any medical professional to catch oral diseases earlier.

4Degrees

Data Products LLC

Crunchbase Website Twitter Facebook Linkedin

Data Science Consulting

4Degrees

Ameex Technologies

Crunchbase Website Twitter Facebook Linkedin

Ameex Technologies is a Digital Transformation partner delivering AI enabled content and personalized commerce solutions.

4Degrees

Ashling Partners

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Ashling Partners is an award-winning service provider in the rapidly growing intelligent automation market.

4Degrees

Sensefolio

Crunchbase Website Twitter Facebook Linkedin

Artificial Intelligence ESG Data startup specialized in socially responsible investment #AI #ESG #SRI #AM #FinTech

4Degrees

10th Magnitude

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10th Magnitude is a Digital Transformation services firm, helping organizations innovate, lead, and disrupt.

4Degrees

AiRo Digital Labs

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AiRo Digital Labs is an emerging tech solutioning company specializing in transforming healthcare ecosystem

4Degrees

Powerupcloud Technologies

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Powerupcloud is a cloud technology company with product & services in cloud migrations, managed cloud and AI solutions.

4Degrees

Socian Technologies

Crunchbase Website Twitter Facebook Linkedin

SaaS, Hardware, Software

4Degrees

SmarterCloud

Crunchbase Website Twitter Facebook Linkedin

SmarterCloud is a cybersecurity platform that isolates and secures customer data.

4Degrees

Ensar Solutions

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Ensar Solutions is an IT Services firm focusing on Data Science & Engineering, Mobile, Analytics, AI, Cloud, software & Security solutions.

4Degrees

Kogentix

Crunchbase Website Twitter Facebook Linkedin

Kogentix is an artificial intelligence and big data software and services firm.

4Degrees

Zuci Systems

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Zuci is revolutionizing the way software platforms are engineered with the help of patented AI and deep learning models.

4Degrees

Strong Analytics

Crunchbase Website Twitter Facebook Linkedin

Data Science & Machine Learning Consultancy

4Degrees

Intelligent Flying Machines, Inc.

Crunchbase Website Twitter Facebook Linkedin

Intelligent Flying Machines develops systems that maximize inventory accuracy and unleash productivity in the workforce.

4Degrees

HoloSurgical Inc.

Crunchbase Website Twitter Facebook Linkedin

HOLOSURGICAL is a Digital Surgery company focused on improving patient outcomes by bringing machine learning to the operating room

4Degrees

Qlarity Imaging

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Qlarity Imaging offers AI to improve patient care by enhancing the diagnostic insights available to radiologists.

4Degrees

CogniSure

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CogniSure unlock the insights buries in unstructured documents using AI platform.

4Degrees

Nala Robotics

Crunchbase Website Twitter Facebook Linkedin

An AI powered robotic restaurant

4Degrees

Shortest Track Company

Crunchbase Website Twitter Facebook Linkedin

Shortest Track manages and accelerates the intelligence supply chain for business executives.

4Degrees

GENINVO

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GenInvo provides software development covering data anonymization, document management, AI & machine learning for the life science industry.

4Degrees

Potentia Analytics

Crunchbase Website Twitter Facebook Linkedin

SAAS, Healthcare: Command Center, Patient Flow Optimization, Provider Scheduling | Policy and Decision Making: Predictive Analytics

4Degrees

BotPenguin

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BotPenguin is an AI-powered chatbot platform.

4Degrees

Ready Networks

Crunchbase Website Twitter Facebook Linkedin

Ready Networks is a cloud service provider that offers DevOps automation, artificial intelligence, data analytics & cloud security services.

4Degrees

Riviter

Crunchbase Website Twitter Facebook Linkedin

Riviter helps brands see and serve the people who love them with AI- and visual search-powered intelligence from social images and video.

4Degrees

Tercero Technologies

Crunchbase Website Twitter Facebook Linkedin

Advanced Edge Artificial Intelligence

4Degrees

Neural Trend

Crunchbase Website Twitter Facebook Linkedin

Neural Trend is an AI + big data to shorten the gap between retail supply and consumer demand.

4Degrees

Altris.AI

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SaaS, Mobile App, ophthalmology deep learning platform for automatic, quantitative analysis and detection retinal diseases.

4Degrees

LAGOM

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At LAGOM, we are working for making the world a better place with the power of AI and high technologies.

4Degrees

DemandWorks Media

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DemandWorks’ unique lead generation programs enable you to deliver your content, to the right buyer, at the right time, on any device.

4Degrees

GliaLab

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GliaLab is develop innovative data-driven AI technology solutions for the healthcare industry and beyond.

4Degrees

7QUBES

Crunchbase Website Twitter Facebook Linkedin

SaaS, FinTech, Distributed Ledger Technology, Blockchain, AI

4Degrees

Nousot

Crunchbase Website Twitter Facebook Linkedin

Nousot develops machine learning products to deliver predictive analytics as a service in the field of data science.

4Degrees

Alli AI for SEO

Crunchbase Website Twitter Facebook Linkedin

Alli is the world’s first Artificial Intelligence for SEO

4Degrees

Menerva Software

Crunchbase Website Twitter Facebook Linkedin

Building AI-enabled lending solutions for Banks and Credit Unions

4Degrees

Bounte

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BOUNTE is an intelligent lost and found app and web platform that modernizes and streamlines the lost and found operations for hotels

4Degrees

StreamAI

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StreamAI builds innovative, solutions-focused AI for the Enterprise. Tools, not toys.

4Degrees

Cognitive AI Technologies

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Cognitive AI Technologies develops Carloudy, a head-up display for cars.

4Degrees

FreightFriend

Crunchbase Website Twitter Facebook Linkedin

Cloud-based, AI-powered truckload procurement software

4Degrees

Talent Intelligence

Crunchbase Website Twitter Facebook Linkedin

Talent Intelligence is now recruiting recent college grads for full-time Research positions.

4Degrees

DaVinci

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Hardware, Flying Taxi, Transportation, AI, Autonomous Vehicles

4Degrees

Logic Pursuits

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Logic Pursuits is an analytics company and premier artificial intelligence solutions provider.

4Degrees

INTELLIC.AI

Crunchbase Website Twitter Facebook Linkedin

Saas, Clinical Data, Clinical Prediction Models, Validation, Development, Intelligence, Predictive Analytics

4Degrees

Entrigna

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Entrigna offers RTES, a real time expert system platform that translates complex data and predictive analytics into actionable insights.

4Degrees

IPgallery

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Founded in 2000, IPgallery is a software development and integration company.

4Degrees

mHealthCoach

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mHealthCoach is a care coordination smart platform that enables physician practices to improve revenue and patient outcomes in the process.

4Degrees

JDK Technologies

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JDK Technologies specializes in web apps, mobile apps, security, IoT, e-commerce, AI, data analytics, document management & cloud solutions.

4Degrees

Zenn.ai

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AI-Powered Deal Execution Technology for B2B Sales Teams

4Degrees

Aboriginal Armadillo

Crunchbase Website Twitter Facebook Linkedin

Startup focused on Natural Language Generation and Image Processing.

Written by Mark Smith

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